The INQUIMUS 2018 Workshop illustrates and discusses how quantitative and qualitative assessment methods could boost a transition toward a new generation of multi-hazard risk, vulnerability and resilience assessments. Particular attention will be paid to complex systems and network sciences’ methods (e.g. Bayesian networks, system dynamics, agent based models, machine learning) and to innovative digital technologies (e.g. big data applications, social media analytics, geospatial visualization tools) unlocking new knowledge and improving the understanding, analysis, communication and validation of risk information.